Endocrine Abstracts

Background: The results of studies evaluating the relationship between serum 25-hydroxyvitamin D (25OHD) with intact PTH (iPTH), calcium (Ca) and phosphorus (P) levels are controversial.Objective: To determine the diagnostic values of iPTH, Ca and P for the prediction of vitamin D deficiency.Methods: We analysed iPTH, Ca and P levels in otherwise healthy 700 subjects (619 (88.4%) female, 81 (11.6%) male, mean age 47.44±16.58 y...

Purpose: The aim of this study was to evaluate the functional status and growth rates of adrenal incidentalomas, diagnosed at our center between 2005 through 2010.Methods: The computer and archive records of 113 patients, diagnosed as adrenal incidentalomas and followed-up at our center, were retrospectively analysed.Results: A total of 113 patients (133 tumors, 80 women (%70.8) and 33 men (% 29.2), ranged in age between 27 and 77 ...

Introduction: Elephantiasis nostras verrucosa (ENV) is a rare, chronic, deforming disorder characterized by hyperkeratosis and papillomatosis of the epidermis with underlying woody fibrosis of the dermis and subcutaneous tissue resulting from chronic nonfilarial lymphoedema. Lymphatic obstruction can be primary or due to various causes such as surgery, tumour, radiation, congestive heart failure or obesity. However, to the best of our knowledge, it has not been reported as a p...

Introduction: Evidence suggests a relationship between high tumoral Ki-67 LI with persistence of tumor after surgery and lower response rate to medical therapy. Therefore, we aimed to determine the relationship between Ki-67 LI and p53 with age, gender, number of surgeries, cure after surgery and cavernous sinus invasion in pituitary adenomas of patients with acromegaly.Methods: The paraffin-embedded tissue sections of 30 patiets with acromegaly, operate...

Introduction: Impaired glucose tolerance and diabetes mellitus are frequently seen complications of acromegaly. Insulin resistance due to chronic growth hormone (GH) excess and inhibition of insulin and glucagon secretion by long-acting somatostatin analogues (SA) used in the treatment are the main reasons of the impaired glucose tolerance.Objective: To determine the effect of long-acting SA treatment on glucose homeostasis regarding the insulin resistan...